IFNG and lung cancer: When PTA- or ZOL-pulsed lung cancer cells were incubated with Vγ2Vδ2 T cells, IFN-γ was secreted from Vγ2Vδ2 T cells in a compound dose-dependent manner, in which the drug concentrations required for the half-maximal IFN-γ production were 10–30 nM for PTA and 100–300 μM for ZOL (Figure 5A), consistent with the results observed in cellular cytotoxicity assay.