CDC6 and papillary renal cell carcinoma: As shown in Supplementary Figure 3B, renal clear cell patients with higher CDC6 expression had a poor prognosis than patients with lower CDC6 expression (P = 4.32e-07). Similarly, higher expression of CDC6 also predicted poor prognosis in patients with renal papillary cell carcinoma (P = 2.03e-05) (Supplementary Figure 3C).