TARDBP and amyotrophic lateral sclerosis: Evidence suggests that ARpolyQ, SOD1, TDP-43, and its ALS associated fragments, as well as other ALS-proteins, including at least one out of five DPRs of C9orf72, are processed via the proteasome (Rusmini et al., 2007, 2010, 2011, 2013, 2019; Sau et al., 2007; Crippa et al., 2010b, 2016a; Onesto et al., 2011; Cristofani et al., 2017, 2018; Cicardi et al., 2018, 2019).