LAMA2 and lissencephaly spectrum disorders: While not as universal as white matter abnormalities, epilepsy and cortical dysplasias (i.e., polymicrogyria and lissencephaly) also occur in patients with MDC1A (Herrmann et al., 1996; Brett et al., 1998; Vigliano et al., 2009; Geranmayeh et al., 2010; Gavassini et al., 2011; Marques et al., 2014).