To date, clinically available nanodrugs for cancer treatment such as Abraxance (albumin-bound paclitaxel) and Vyxeos (lioposomal daunorubicin and cytarabine) are applied in R/M HNSCC, breast, lung, and pancreatic cancer, metastatic breast cancer and high-risk acute myeloid leukemia 47, 80, 81. The gene discussed is ALB; the disease is head and neck squamous cell carcinoma.