CASP3 and bronchiolitis obliterans syndrome: The expression of cleaved-caspase-3 was also significantly increased in the BO group (Control (n = 8) vs. BO (n = 7); 1.0 ± 0.1 vs. 1.4 ± 0.1 A.U., P < 0.001 vs. Control), and again propranolol blocked the increase (BO (n = 7) vs. Pro + BO (n = 9); 1.4 ± 0.1 vs. 1.1 ± 0.2 A.U., P < 0.01 vs. Control) (Fig. 4F).