Phospho-RyR2 (Ser-2814) was significantly increased in the atrium of the BO group (Control (n = 12) vs. BO (n = 9): 1.0 ± 0.2 vs. 1.5 ± 0.4 A.U., P < 0.01 vs. Control), and this increase was blocked by propranolol (BO (n = 9) vs. Pro + BO (n = 13): 1.5 ± 0.4 vs. 1.2 ± 0.3 A.U. P < 0.05) (Fig. 4C). The gene discussed is RYR2; the disease is bronchiolitis obliterans syndrome.