ACAN and neoplasm: hASCs cells in the stimulation group and control group were collected, and RT-PCR was used to detect osteogenic differentiation genes (Runx2, OCN), chondrogenic differentiation genes (ACAN, COMP, SOX9), adipogenic differentiation genes (PPARG), paracrine genes (VEGF, TB4, McP-1, and SDF-1α), proliferative signaling pathway genes (CyclinD1, c-myc, LRP5), and tumor-related genes (BMI-1), respectively.