Further even though the cancer cell lines used in this study variably expressed FGFR1-4 (Supplementary Fig. 7c), neither BGJ398 nor recombinant FGF2 in tissue culture altered the best described downstream mediators of FGFR signalling, pERK and pAKT (Supplementary Fig. 7d, e). The gene discussed is FGFR1; the disease is cancer.