Secondly, we assessed the 14 proteins (APOL1, C7, COMP, CKM, CRTAC1, CTSH, EFEMP1, FBLN1, GSN, HSPG2, IGHG1, IGKC, SHBG, MYH2) that were significantly altered in ALS by Bioprofiling and STRING. This evidence concerns the gene FBLN1 and amyotrophic lateral sclerosis.