For a more in-depth analysis of in vivo TXNIP expression, we next evaluated 127 RNA-seq datasets that were recently generated on macrodissected tissue sections sampled from multiple regions of primary tumor (n = 95) that were matched with individual liver metastases (n = 32) within the same individual patient(s) of a separate rapid autopsy cohort (n = 10 total patients)10,33. The gene discussed is TXNIP; the disease is neoplasm.