CD34 and acute myeloid leukemia: To address this question, AML blasts (from peripheral blood; Supplementary Table 1) and normal hematopoietic cells (peripheral blood mononuclear cells (PBMC) and CD34+ cells; Supplementary Table 2) were first treated with a low concentration of etomoxir (Etx, 3 μM) to prevent the entry of FFAs into mitochondria by blocking the activity of carnitine palmitoyl transferase 1, and oxygen consumption rate (OCR) was evaluated by Seahorse analysis.