The global MACE criterion was associated with MetS in univariate (OR 2.13; 95CI 1.56–2.92; p <  0.01) as well as multivariate analysis (OR 1.85; 95CI 1.24–2.75; p <  0.01) after adjustment for diabetes, LDL-cholesterol, smoking, age, sex, BMI, statin treatment and serum albumin (Table 4). The gene discussed is ALB; the disease is diabetes mellitus.