Worsening of visual function is a common feature of AD, [8] and the accumulation of Aβ plaques and aggregates of hyperphosphorylated tau in the visual association cortices, [9,10] primary visual cortex, [11,12] lateral geniculate nuclei, [13,14] and the retina [15–17] has been reported. The gene discussed is MAPT; the disease is Alzheimer disease.