Moreover, because increased expression of either RAB1A or RAB1B has been found in several types of cancer, including prostate cancer [65], hepatocellular carcinoma [66–68] and colorectal carcinoma [69, 70], it would be not surprising if their effects are synergistic with that of overexpressed GOLPH3. This evidence concerns the gene GOLPH3 and hepatocellular carcinoma.