Interestingly, the overexpression of the Golgi phosphatidylinositol transfer protein PITPNC1 in breast cancer cell lines promotes the formation of a protein complex with RAB1B, which subsequently seems to recruit GOLPH3 to the Golgi, resulting in enhanced secretion of pro-invasive and pro-metastatic mediators [63]. The gene discussed is PITPNC1; the disease is breast carcinoma.