In PLum-AD cells, while the untreated cells primarily expressed CK8 with an average of 97.89 ± 0.32%, the expression of CK8 increased to 99.19 ± 0.81% upon treatment with SB203580 and decreased tremendously and significantly to 89.23 ± 2.22% (p-value < 0.001) when treated with IL-6. Here, IL6 is linked to Alzheimer disease.