KLK3 and posterior cortical atrophy: Given the inconsistent findings and potential study biases, most professional organizations, including the American Urological Association [7], United States Preventive Services Task Force [8], American Cancer Society(ACS) [9], and National Comprehensive Cancer Network [10] generally recommend shared decision-making about undergoing PSA testing for men in the general population at average risk of PCa at age 55 up to age 69 (age 50 for ACS).