To understand the role of endothelial cell HSPA12B and YAP in the regulation of angiogenesis in vivo, we induced MI in WT and endothelial cell–specific Hspa12b deficient (eHspa12b–/–) or YAP (eYap–/–) mice and examined cardiac angiogenesis 28 days after MI. The gene discussed is HSPA12B; the disease is myocardial infarction.