Figure 8A shows that the positive immunofluorescence staining of CD31 were markedly decreased in the eYap–/– MI hearts compared with WT MI hearts. In addition, the levels of angiogenetic factors such as Ang1, VEGF, and VEGFR2 in the myocardium of eYap–/– MI mice were significantly lower than those in WT MI hearts (Figure 8B). The gene discussed is ANGPT1; the disease is myocardial infarction.