As an important receptor for VEGF signal transduction, the vascular endothelial growth factor receptor-2 (VEGFR-2) encoded by KDR, highly expressed in most tumors, can not only promote the proliferation of vascular endothelial cells, induce angiogenesis around tumor tissue, but also accelerate the migration of cancer cells 25, 26. The gene discussed is KDR; the disease is cancer.