HGF and gastric cancer: To explore the relationship between HGF and c-MET mRNA expression and prognosis of gastric cancer patients, the TCGA database was utilized and results demonstrated that HGF high expressed, and both HGF and MET high expressed gastric cancer patients have relatively shorter overall survival time, though the prognostic value of single marker “MET” in gastric cancer patients was marginal significant (TCGA/HGF: HR = 1.51 (1.08-2.12), P = 0.015, TCGA/MET: HR = 1.46 (0.98-2.18), P = 0.059, and TCGA/HGF&MET: HR = 1.51 (1.02-2.25), P = 0.039; Figure 2A-C).