Neonatal Sepsis is the commonest cause of neonatal mortality and morbidity resulting in 30-50% of total neonatal deaths in developing countries.16,17 Considering its high mortality and morbidity, a specifc diagnostic marker eg. Interleukin 6, Interleukin 8, Procalcitonin with high sensitivity and specifcity is desirable in neonatal sepsis. The gene discussed is IL6; the disease is Neonatal sepsis.