MYCN and neuroblastoma: The analysis by employing the software of miRanda illustrated that the region of 506–511 on the 3′-UTR of MYCN, and miR-98 directly bound to MYCN 3′-UTR and decreased MYCN expression, whereas over-expression of MYCN rescued the decreased malignant phenotype caused by over-expression of miR-98 in NB, indicating that miR-98 indeed participates in NB by regulating cell proliferation, cell clone formation and migration.