By observing myocardium with ischemia–RA, we found that the expression, distribution, and phosphatization states of Cx43 are all changed to different extents to reduce the conduction velocity of myocardium and increase the probability of formation of RA [12]; however, the specific correlation between Cx43 and miRNAs in hypothermic ischemia–RA has not been clarified. This evidence concerns the gene GJA1 and ischemia.