Of the 52 T1D patients and 55 healthy controls enrolled for flow cytometry analysis, the expression of B7-H3 on CD14+ monocytes was significantly higher in T1D patients (13.913 ± 8.640 vs 10.142 ± 4.596, P = 0.0295) (Fig. 1a). This evidence concerns the gene CD276 and type 1 diabetes mellitus.