IGFBP2 and breast cancer: In addition to the adipokines mentioned above, there are exceptional multiple adipokines involved in the interaction between CAAs and BC cells, including resistin, insulin-like growth factor 1 (IGF-1), hepatocyte growth factor (HGF), platelet-derived growth factor-BB (PDGF-BB), insulin-like growth factor binding protein 2 (IGFBP-2), IL-1β, IL-8, TNF-α, granulocyte colony-stimulating factor (G-CSF), vascular endothelial growth factor (VEGF) and autotaxin (ATX), lysophosphatidic acid (LPA).