PRNP and aceruloplasminemia: We would like to suggest modifying the previously proposed MM2c-sCJD diagnostic criteria to the following [4]: (1) slow-progressing dementia, (2) methionine homozygosity at codon 129 of the PRNP gene without mutations, (3) DWI showing hyperintensities confined to the cortex of the brain, (4) delayed onset, (5) focal discharges on EEG, and (6) no more than two out of the following four clinical features within 6 months after onset – (a) myoclonus, (b) pyramidal or extrapyramidal sign, (c) cerebellar ataxia or visual impairment, and (d) akinetic mutism.