Two categories of genes that could be further examined in combination with MIA are susceptibility factors that do not recapitulate all core symptoms of autism when manipulated alone ((FMRP translational regulator 1 (FMR1), methyl CpG binding protein 2 (MECP2)) and immune-related genes associated with ASD (human leukocyte antigen (HLA), phosphatase and tensin homolog (PTEN)). The gene discussed is PTEN; the disease is autism.