TP53 and cancer: Based on Wikipathways and KEGG pathways enrichment analysis of module 1, the top five enriched pathways from either database were the cell cycle, progesterone-mediated oocyte maturation, oocyte meiosis, p53 signaling pathway, cellular senescence, regulation of sister chromatid separation at the metaphase–anaphase transition, retinoblastoma gene in cancer, gastric cancer network 1 and ATM signaling pathway.