TP53 and fleck corneal dystrophy: In the present study, we also noted the upregulation of miR-132, together with three other miRNAs (miR194-2, miR15a, and miR-145) that downregulated some important genes’ expression, including CDKN1A, REL, CCND1, CDK6, FGF2, SOX5, BDNF, SK1, BMI1, and TP53. Considering genes’ interaction in networks, the inhibition of these important genes’ expression may involve some risk pathways that contributed to pathogenesis and epileptogenesis in patients with FCD and refractory epilepsy.