SNCA and Parkinson disease: Mutations in genes associated with inherited PD, such as PARK2 (Parkin), PINK1, PARK7 (DJ-1), alpha-synuclein (SNCA), GBA1, and leucine-rich repeat kinase 2 (LRRK2), have been observed to be related to mitochondrial homeostasis [3,7,10,11,15].