The male patients with oral cancer and the rs11705701 GA+AA, rs4402960 GT+TT, and rs1470579 AC+CC genotypes exhibited higher risk of advanced clinical stage, larger tumor, and progression of lymph node metastasis compared with those with the IGF2BP2 rs11705701 GG, rs4402960 GG, and rs1470579 AA genotypes (Table 3, Table 4 and Table 5). This evidence concerns the gene IGF2BP2 and lip and oral cavity carcinoma.