In contrast, cancers displaying favorable risk with high ALT (GBM and LIHC) may be regulated by E2F4, TFDP1, FOXM1, E2F7, SIN3A, E2F1, MYBL2, and E2F2 (FDR = 0.0001) (Figure 4b). The gene discussed is E2F1; the disease is glioblastoma.