To explore the roles of the miR-493-5p/ITGB1 axis in NR2F1-AS1-mediated aggressive phenotypes of NSCLC cells, si-NR2F1-AS1-treated H460 and A549 cells were further transfected with an miR-493-5p inhibitor or NC inhibitor. The gene discussed is ITGB1; the disease is non-small cell lung carcinoma.