Studies on sheep or pigs also reported that angiotensin II did not worsen the ATP level [7], medullary hypoxia [8], and mitochondrial respiration [9] during sepsis, suggesting that the vasoconstrictive effects of angiotensin II on the efferent arteriole might not induce reductions in blood supply to the peritubular capillaries. This evidence concerns the gene AGT and Sepsis.