ARBs: angiotensin receptor blockers; CCBs: calcium channel blockers; CKD: chronic kidney disease; DM: diabetes mellitus; DPP4: dipeptidyl peptidase 4; eGFR: epidermal growth factor receptor; F: female; M: male; SD: standard deviation; SGLT2: sodium-glucose cotransporter-2. The gene discussed is EGFR; the disease is chronic kidney disease.