CDH1 and neoplasm: “E-cadherin (epithelial cadherin) is a polypeptide protein that belongs to function is to facilitate cell-cell adhesion and recognition. E-cadherin has morphogenesis of cells during migration and acts as a tumor suppressor gene” [18]. In some solid tumors, such as breast cancer, loss of E-cadherin function is often associated with more invasive disease [19].