The magnitude of the reduction in Myh7/Myh6 ratio was larger in presence of diabetes (diff-in-diff: − 1.01 [− 1.73, − 0.29], PN = 0.995), whereas Nppa mRNA levels did not differ (diff-in-diff: − 0.21 [− 0.71, 0.28]). Here, MYH6 is linked to diabetes mellitus.