GPT and hepatocellular carcinoma: However, when PIVKA-II combined withγ-GT/ALT ratio was used to diagnose HBVDNA−/HCC, the AUROC of PIVKA-II increased (0.902 and 0.895, respectively).There were no significant differences in AUROCs between combined diagnosis and single diagnosis (P = 0.283, P = 0.767, respectively).