Infection of the transfected cells with P. berghei sporozoites revealed that replacement of the AA 193–203 sequence of mSR-B1 by that of hSR-B1 in the D2 chimera resulted in a twofold increase in P. berghei infection in CD81KOH16 cells (Fig. 6e). The gene discussed is MSRB1; the disease is infection.