Immunophenotyping analysis of B16IDO and B16TDO tumors revealed an upregulation of AHR expression in tumor-infiltrating myeloid-cell populations, such as Ly6C+ Monocytes (CD11b+Ly6ChighLy6G−), conventional DCs (CD11b+CD11c+), polymorphonuclear cells (CD11b+Ly6G+Ly6Clow) and particularly TAMs in comparison to B16WT tumors (Supplementary Fig. 3e). This evidence concerns the gene AHR and neoplasm.