Other proofs of the involvement of CD36 and TSP-1 were provided for the decrease of protein expression of CD36 in colon cancer (with progression of the decrease from adenoma to carcinoma) and provided insights on the roles of CD36 as suppressor of the β-catenin/c-myc signaling by promotion of proteasome-dependent ubiquitination of GPC4 [206]. This evidence concerns the gene CD36 and adenoma.