ADGRE2 and familial pancreatic carcinoma: Furthermore, Vogl et al. [94] revealed that the levels of CD97, CD274, and CD276 assessed by ELISA could serve as readily measurable prognostic or predictive markers in patients with advanced disease or metastatic breast, colon, or pancreatic cancer, being at baseline before cytotoxic treatment, and during the course of the chemotherapy, as well.