To explore the effects of FGFR4 polymorphisms on lung adenocarcinoma risk, a whole-blood specimen from each of the 277 patients was collected and examined for genotype frequencies of the four FGFR4 SNPs (rs2011077, rs351855, rs7708357, and rs1966265). The gene discussed is FGFR4; the disease is lung adenocarcinoma.