It also increases the expression of CCL26/eotaxin-3 and CCL24/eotaxin-2 in SK-Hep-1, Hep 3B HepG2, and MHCC-97L hepatocellular carcinoma [2,143], although in this tumor, this effect may depend on the model because, in another study, hypoxia in the HL-7702 and Huh-7 lines did not change the expression of these chemokines [193]. This evidence concerns the gene CCL24 and hepatocellular carcinoma.