This mechanism may be important in cycling hypoxia-induced TAM recruitment, although further research is required to better understand the impact of cycling hypoxia on neoplastic processes involving CCL15/HCC-2 in hepatocellular carcinoma and colorectal cancer, i.e., organs with a high expression of CCL15/HCC-2 [147]. The gene discussed is CCL15; the disease is hepatocellular carcinoma.