In the present study, a diagnosis of cachexia was simply determined to meet BMI < 20 kg/m2, FFMI (≤17.4 kg/m2 for males and ≤15 kg/m2 for females) [26], and at least two additional biochemical criteria (Hb level < 12 g/dL, CRP level < 5 mg/dL, Alb level < 3.2 g/dL). The gene discussed is ALB; the disease is Cachexia.