EPCAM and congenital diarrhea 5 with tufting enteropathy: Truncating and null mutations of EpCAM in humans and mice cause congenital tufting enteropathy (CTE), a severe diarrheal disorder characterized by epithelial dysplasia, compromised intestinal barrier, failure to thrive, and, in mice, post-natal demise within the first week of life [9,10].