A similar trend was observed in ASXL1, DNMT3A, EZH2, IDH1/2, and TET2 in the serial single gene sequencing study of 40 ET and 43 PV JAK2V617F patients by Quintas-Cardama et al., however, statistical significance was not achieved [198]. Here, ASXL1 is linked to essential thrombocythemia.