A particularly interesting finding is the fact that the Eph genes EphA2, EphA8 and EphB2 are located within the murine Athsq1 (atherosclerosis) susceptibility locus [100], which is highly homologous to the premature myocardial infarction susceptibility locus in humans that similarly contains EphA2, EphA8 and EphB2 [101]. Here, EPHA2 is linked to atherosclerosis.