The hallmarks of AT inflammation are influx of macrophages, cluster of differentiation 4–positive (CD4+) and CD8+ T cells, dendritic cells, and natural killer (NK) cells and increased expression of cytokines/chemokines.(16) Primary cues in AT inflammation remain poorly explored but arguably involve diet‐induced stress of adipocytes, which subsequently induces a cytokine and chemokine response and immune cell infiltration. This evidence concerns the gene CD4 and ataxia telangiectasia.