Overexpression of Lysyl oxidase-like 2 (LOXL2) enhances EMT-like process and increases migratory activity in PDA cells [97], whereas inhibition of FAK by a small-molecule inhibitor of tyrosine kinases FAK/PYK2 inhibits the same process in PDA cells [101]. This evidence concerns the gene PTK2 and Patent ductus arteriosus.