HPGD and neoplasm: Their analysis revealed 29 genes potentially contributing to the metastatic process including β-catenin which plays role in cell adhesion/EMT, acidic nuclear phosphoprotein 32 family member A (ANP32A) which is a tumor suppressor, 15-hydroxyprostaglandin dehydrogenase (HPGD), SET nuclear proto-oncogene (SET), and Sp1 transcription factor (SP1) [139].