HLA-G and carpal tunnel syndrome: β2-microglobulin amyloid deposits are another proposed aetiological factor in CTS with AVF and was found in all biopsied samples after surgical decompression in 1 study of 21 patients.24 β2-microglobulin deposition causes inflammation which leads to adhesions and oedema that in turn mechanically compress the median nerve, in dialysis independent of vascular access type.