In this experimental study, effective lncRNAs and genes were predicted from different criteriafor renal cell carcinoma (RCC) by bioinformatics methods and lncRNA-miRNA-mRNA interaction was constructed; thenthe effect of Staphylococcus aureus tst gene on induction of apoptosis pathways on ACHN and HDF cell lines wasinvestigated. Here, TST is linked to hereditary clear cell renal cell carcinoma.